In the past year, weight loss drugs have had a 'revolution'. And it's all thanks to a specific injectable medication, originally designed for people suffering from diabetes.
As you're likely aware, celebrities, influencers, models and those in elite social circles made the popularity of the drug go mainstream earlier this year, with The Guardian describing it as 'Hollywood's worst-kept secret'.
While only a few celebrities have publicly admitted to taking the drug, others have shared their views on the trend, with some openly denying taking it.
For the most part, the celebrity commentary that does exist around the weight loss drug is somewhat negative. Especially when it comes to the long-term side effects.
Chelsea Handler "didn't know" she was on it. Sharon Osbourne "felt f**king s**t" on it. Amy Schumer said she was so ill she couldn't play with her son.
But there's no one who could've flipped the conversation around weight, willpower and prescription weight-loss drugs quite like Oprah Winfrey.
Watch: Markle and Prince Harry with Oprah Winfrey. Post continues below.
For the unaware, Oprah had, and continues to have, a long and very public relationship with her own weight. It was a subject she often tackled on The Oprah Winfrey Show and in O! magazine.
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