This post deals with the topic of addiction and might be triggering for some readers.
Over the course of her career, Minnelli has won four Tony Awards, two Grammys, and an Emmy and Oscar.
But it was something in particular that caught the audience's attention: the fact Minnelli was in a wheelchair and struggling with her mobility.
Watch: Celebrities, on their Oscars speeches. Post continues below.
Minnelli, alongside Lady Gaga, presented the Best Picture award - aka the evening's biggest winner CODA.
The crowd cheered when the pair came on stage, prompting Gaga to say: "Do you see that [Liza]? The public, they love you."
As Minnelli sorted through her notes and said "I don't understand," Gaga told her, "I got it." And in a special moment captured just beforehand, Gaga said to her co-presenter, "I got you", to which Minnelli responded "I know".
It was also a momentous occasion for Minnelli, who was celebrating her 50th anniversary of the film Cabaret in 1972.
It's not the first time that Minnelli has experienced poor health.