Every year, hundreds of Australian women will experience recurrent miscarriage. And while many will never receive answers about the cause of their pregnancy loss, a handful will be given a little known diagnosis: Antiphospholipid Antibody Syndrome.
But it’s not just women who experience APS. Often known as Hughes Syndrome or Sticky Blood Syndrome, this lifelong disease and its potentially deadly symptoms can be experienced by men as well.
So what is Antiphospholipid Syndrome? What causes it? And is there treatment available?
Let’s break it down.
What is Antiphospholipid Syndrome?
APS is an autoimmune disorder in which abnormal proteins, called antibodies, attack platelets in the blood causing them to clump together. People with APS have thickened circulating blood and are more likely to experience potentially dangerous clots in their veins, blood vessels and organs.
There are two types of Antiphospholipid Syndrome. The most common is Primary APS, in which the condition occurs on its own. The other is Secondary APS, in which it occurs in association with another health problem, such as Systemic Lupus.
There is no cure for Antiphospholipid Syndrome, but treatments are available that significantly reduce the risk of complications.
What causes Antiphospholipid Syndrome?
The cause of Antiphospholipid Syndrome is unknown. But according to Dr Talat Uppal, an obstetrician and clinical senior lecturer at the University of Sydney, women are between three to five times more likely to be diagnosed with the condition than men. Most cases, she says, tend to occur among people aged between 30 and 50.
What are the symptoms of Antiphospholipid Syndrome?
Without treatment, the most common symptoms of APS include:
- Blood clots, which can lead to heart attack, stroke or pulmonary embolism (blockage in the arteries that supply blood to the lungs).
- Migraine headaches.
- Low blood platelet count.
- Mottled skin tone; a purplish lace-like purplish pattern on the skin.
- Miscarriage and pregnancy complications.
As Dr Uppal explains, “APS generally either gets picked up because somebody has a family history; for example, someone’s sister had a clot so therefore they get screened. Or because a woman has had recurrent miscarriages, that is three consecutive miscarriages in the first trimester.”
Mia Freeman talks about feeling lost after miscarriage…