"She was here today." Thousands run in Sydney to support cancer charity Love Your Sister.

He’s not into hocus pocus, but Gold Logie winner Samuel Johnson felt his late sister Connie by his side as a sea of rainbows took over Sydney Harbour.

More than 7000 people, many adorned with rainbow clothing in support of cancer research charity Love Your Sister, took part in a 10 and five kilometre run across the coathanger on Sunday.

Johnson and sister Hilde led the rainbow charge in honour of Connie, who died last September after a long battle with cancer.

“We covered Sydney Harbour with rainbows this morning and we came good in our promise to vanquish cancer with joy,” Johnson told AAP after the race.

“I’m not spiritual, I’m not into any hocus pocus, but she was here today and her essence was everywhere to be found.

“Her legacy is well and truly alive.”

Connie was awarded the Medal of the Order of Australia the day before she died for her work on behalf of cancer patients, including the establishment of the Love Your Sister charity.

Sunday’s run raised close to $250,000 and Johnson says he’s edging closer to his goal of fundraising $10 million.

“If we raise $320,000 we’re going to crack $8 million,” he said.

Johnson quit acting in 2016 to focus on the cancer charity and was named as Victoria’s Australian of the Year just weeks after Connie died.

Listen to Mia Freedman’s interview with Samuel Johnson. Post continues after audio.