Karl Stefanovic has split from his wife of 21 years.

Breakfast television host Karl Stefanovic has split from his wife after 21-years of marriage.

News Corp reported Stefanovic, 42, has moved out of the family home he shared with wife, Cassandra Thorburn, 44, and their three children.

The presenter is said to be currently staying at business mogul James Packer’s Bondi apartment.

The split comes only one year after the presenter spoke publicly about their relationship.

karl stefanovic reportedly splits

Karl and Cassandra at the 2011 Logies. Image via Getty.

Stefanovic told The Daily Telegraph in 2015 Thorburn had sacrificed her own career to support their budding family.

“She gave up a promising career at the ABC and I’m forever thankful and tremendously appreciative of that,” he says.

“Cass wanted to be at home, and wants to be there now, and we’re very lucky to be in a financial position where we can do that."

“But should she ever want to go back to work, then of course she can."

The pair were snapped happily sitting together at a Mercedes Benz Fashion Week show in May.

Stefanovic is yet to publicly comment on the split.

Scroll through to see some of our favourite Karl moments. Images via Facebook. (Post continues after gallery.)