During this campaign, a photo came to symbolise the fight for access to this basic procedure and the women behind it.
But it might surprise all those who have been sharing it on social media these past few weeks that the photo was actually taken in 2016 - before the referendum was even announced.
The photographer Alastair Moore and the photo's feature subject - Hannah Little - have shared the story behind this powerful image.
Hannah - the woman in the orange jumper - organised the march of 77 women holding suitcases to symbolise the nine to 11 women a day who travelled from Ireland and Northern Ireland, usually to England, to access abortions. It was just one part of a protest involving hundreds of women outside the Irish embassy in London.
"While 35,000 people joined the March for Choice in Dublin, several hundred London-Irish gathered outside the Irish Embassy to demand a repeal of the Eighth Amendment," she told Mamamia on Tuesday.
"We had met at the same spot in 2012 to mourn the loss of Savita Halappanavar, a 31-year-old woman who died in an Irish hospital from a septic miscarriage after being denied a termination."
Hannah told Mamamia that London-Irish Abortion Rights Campaign - the group she co-founded and has been tirelessly campaigning for the referendum - was actually formed out of that protest.
"I booked a room for 30 people in the hope of forming a committee to form the basis of the group. Within 24-hours of announcing our first open meeting, over 300 people had signed up to attend.