The Wedding Singer star, Alexis Arquette, dies age 47.

Transgender actress Alexis Arquette died due to ‘complications related to AIDS’, PEOPLE reports. The 47-year-old’s cause of death was previously unknown.

A source close to the family told the outlet that Alexis “had been suffering for a long time.”

“She was sick for years,” the source reportedly said. “At one point, she wasn’t able to leave the house; she was in bad shape.”

Mamamia previously reported…

Hollywood is in mourning for Alexis Arquette, who died overnight at the age of 47 surrounded by her family and friends.

Known for her roles in The Wedding Singer and Pulp Fiction, Alexis was also a staunch advocate of transgender rights, having herself transitioned in 2001.

The actress died with her favourite song playing in the background as loved ones stood by her bedside. Among them, her famous siblings Patricia, David, Rosanna and Richmond Arquette, who issued a statement via social media overnight describing Alexis as “a force”.

Richmond Arquette's statement about his sister's death. Image: Facebook.

"Our brother Robert, who became our brother Alexis, who became our sister Alexis, who became our brother Alexis, passed this morning September 11, at 12:32 am," Richmond wrote on Facebook.

"He was surrounded by all of his brothers and sisters, one of his nieces and several other loved ones. We were playing music for him and he passed during David Bowie's Starman. As per his wishes, we cheered at the moment that he transitioned to another dimension."

While the cause of Alexis' death was not specified, Richmond expressed the family's gratitude that her passing was "swift and painless", writing, "He died as he lived, on his own terms."

Tributes flowed on social media from fans and celebrities, including Boy George who inspired Alexis' role in the Wedding Singer.

"R.I.P my sister Alexis Arquette," George wrote on Twitter. "Another bright light gone out far too soon. Love to the family and all that loved Alexis."

Patricia Arquette Tweeted links to Starman and T. Rex's Cosmic Dancer in memory of her "first best friend".